Emil Walter Ciurczak

77 Park Rd.

Goldens Bridge, NY 10526

ph:(914) 767-0720 fax:(914) 767-0173 e-mail:emil@ciurczak.com

____________________________________________________________________________________

EDUCATION Rutgers University, Newark, NJ

B.A. in Chemistry, 1970

M.S. in Chemistry, 1974

Ph.D Research in Analytical Chemistry

Applications of the Schoenemann Reaction

Seton Hall University, South Orange, NJ

M.S. in Chemistry, 1998

Ph.D. Research in Analytical Chemistry

Applications of Near-Infrared in HPLC

INDUSTRIAL

EXPERIENCE

Purdue Pharma, LP, Ardsley, NY

6/98 – 12/01 Research Fellow. Group Leader for New Technology Group. Developed and implemented new (non-traditional) instrumentation for process control, physical methods, finished products. Developed biomedical instrumentation and software for commercialization. Methods included: Near-Infrared, UV/Vis, Raman, Fluorescence, Electrochemistry. Supervised group of degreed personnel. Generated six patent applications.

 

Merck & Co., Inc., West Point, PA

6/92 - 9/93 Developmental Chemist. Project leader in development/design of Near-Infrared (NIR) instrumentation for process control applications; instructor in NIR theory and applications at U.S. and PR sites; consultant for NIR projects, improved HPLC methods used for NIR in method calibrations, and wrote methods and protocols for NIR work.

NIRSystems, Inc., Silver Spring, MD

9/91 - 6/92 Applications Scientist. Designed and performed NIR feasibility studies for customer applications; taught basic and advanced NIR courses; responsible for pharmaceutical and physical chemical applications of NIRS; presented experimental results at scientific meetings and conferences

4/89 - 9/91 Technical Consultant. Demonstrated NIR applications for customers; carried out experiments to support physical/chemical uses of NIR published in applications brochures; presentations given at scientific meetings and customer sites

 

Bran & Leubbe, Inc., Elmsford, NY

6/87 - 4/89 Technical Consultant. Developed NIR analyses for physical/analytical applications; consulted in both hardware and software development projects; conducted training sessions for both employees and customers; wrote numerous applications notes

 

Applied Analytical Industries, Inc., Wilmington, NC

5/88 - 9/88 Laboratory Director. Trained and supervised personnel in HPLC theory and practice; restructured operating and reporting system for the laboratory data. (Contract position)

Sandoz Pharmaceuticals, Inc., East Hanover, NJ

7/85 - 6/87 Developmental Scientist III. Methods Development for Quality Assurance; techniques utilized include HPLC, UV/Vis, NIR, FT-IR, GLC, laser particle sizer, thermal analysis (DSC/TGA), atomic absorption, plasma emission, surface area, physical parameters.

4/82 - 7/85 Supervisor. Instrument Group in Quality Assurance; purchased, installed, calibrated, and maintained analytical/physical measurement instrumentation; taught HPLC theory and troubleshooting; supported raw material and in-process areas; introduced NIR as qualitative tool in pharmaceutical analyses. Supervised several degreed personnel.

1/80 - 4/82 Analytical Research Scientist. Developed methods for analyzing/characterizing raw materials, intermediates, and finished pharmaceuticals in support of new products using GC, HPLC, Plasma Emission Spectroscopy, Thermal Analyzer, UV/Vis

Henkel Corporation, Hoboken, NJ

10/77 - 1/80 Laboratory Manager. Developed methods for analysis of surfactants for Analytical Research and Quality Control; provided technical support for both in-process and finished products; supervised eight degreed and non-degreed scientists

Cooper Laboratories (Berlex), Cedar Knolls, NJ

7/73 - 10/77 Senior Analytical Chemist. Designed and ran stability program; developed stability indicating assays; wrote analytical sections of IND and NDA documents; methods utilized included HPLC, DSC/TGA, ion-selective electrodes, polarography, GC; supervised five degreed scientists

CIBA Geigy Pharmaceuticals, Summit, NJ

10/70 - 7/73 Associate Scientist. Performed analyses to support pre-formulation, formulation, and stability studies; developed methods for testing package/product compatibility for Pharmacy Research Division

Riegel Paper, Inc., Milford, NJ

6/70 - 10/70 Junior Chemist. Developed thermal analysis methods to measure rate and degree of cure of thermosetting resins impregnated in filter paper using DSC/DTA

 

TEACHING EXPERIENCE

1/03 – present SPIE, Short Course Instructor, "NIR in Pharmaceutical and Medical Applications", National Meetings

2/01 – Present Center for Professional Advancement, Short Course, "NIR Spectroscopy" (director) and "Practical Problem Solving Chemical Analysis" (instructor): US and Europe.

3/88 – 10/00 American Chemical Society; Short Course (Lead Instructor). Taught "Practical Near-Infrared Analysis" annually at PittCon, ACS National Meetings.

1/98 – 6/98 Mount St. Mary’s College, Emmitsburg, MD; Adjunct Faculty. Taught Quant. Analysis lecture & lab, Instrumental Analysis Lab, and mentored student research.

8/97 - 12/97 Hood College, Frederick, MD; Adjunct Faculty. Taught Quant Anal Lecture and Lab.

9/93 - 5/97 Eleanor Roosevelt High School, Greenbelt, MD; Taught Physics, Chemistry, Chem. Instrumentation, Environ. Science. Mentored student research. {Certified in MD}

1/91 - 5/91 Seton Hall University, South Orange, NJ; Adjunct Faculty (& TA). Taught Chemistry for non-majors, developed labs (Teaching Assistant: Organic Lab)

1/86 - 5/91 College of St. Elizabeth, Convent Station, NJ; Adj. Faculty. Taught Analytical, General Chem. Lab, Instr. Analysis, Phys Chem (Thermo), Gen Physics & Lab. Supervised student research.

8/84 -12/84 Caldwell College, Caldwell, NJ; Adjunct Professor. Taught Physics laboratory.

9/79 - 6/85 New Jersey Institute of Technology, Newark, NJ; (Hudson County CC) Adjunct Professor. Taught Instrument Troubleshooting and Instrumental Analysis

9/79 - 6/85 Stevens Institute of Technology, Hoboken, NJ; (Hudson County CC) Adjunct Professor. Taught Quant. and Instrumental Analysis and Instrument Troubleshooting.

EDITORIAL POSITIONS

3/98 – 4/00 Pharmaceutical Technology. Contributing Editor for "PharmAnalysis" column series on new analytical trends and validation topics for the pharmaceutical industry

1/89 - present Spectroscopy. Contributing Editor for "Molecular Spectroscopy Workbench" column series of articles on spectroscopic technique and theory.

8/86 -12/88 Council for NIR Spectroscopy. Newsletter Editor. As first editor, designed format and wrote newsletters

9/92 - present Journal of Near-Infrared Spectroscopy. Editorial Advisory Board

5/95 – 12/01 Food Testing & Analysis. Editorial Advisory Board

9/02 – present Journal of Process Analytical Chemistry. Pharmaceutical editor

9/02 – present American Pharmaceutical Review. Editorial Advisory Board

MILITARY Veteran, U.S. Army Infantry, 2/67 - 1/69 (SP4); Honorable Discharge

STATUS

PROFESSIONAL Amer. Chem. Soc., Soc. Appl. Spectrosc: Local Chair ‘96-’98, ‘99-’00, ‘03-‘04, ORGANIZATIONS CNIRS, Charter Member, IDRC: Exhibits Chair ’96, co-Chair, ’98, Gen. Chair, ’02.

Proc. Anal. Tech. Validation Working Group (FDA initiative): 2002

PATENTS: US 5,296,843 (1994): "Fluid or Vapor Diagnostic Device"

US 5,691,701 (1997): "Fluid or Vapor Diagnostic Device"

US 6,534,768 (2003): "Hemispherical Detector"

US 6,549,861 (2003): "Automated System and Method for Spectroscopic Analysis"

PUBLICATIONS/ Six texts, two in preparation, four chapters (invited), 30+ published papers,

PRESENTATIONS 100+ presented papers or posters.

AWARDS and Eagle Scout, 1962; "Who’s Who in the East", 1978; "Most Meritorious Paper,

HONORS 1980", Society Cosmetic Chem; Soc. Appl. Spec. (NY Chapter) Award for Graduate Research, 1991; "Who’s Who in Teaching", 1995. "Who’s Who", 1997.

 

PUBLICATIONS:

Texts and Chapters:

Instrument Troubleshooting: A Basic Guide, Stevens Institute of Technology Press, Stevens Tech., Hoboken, NJ, 1981, 2nd edition: 1984.

Handbook of Near-Infrared Analysis, Editor & Author, Marcel-Dekker Inc., New York, 1992. (5th printing) Co-editor: D.A. Burns.

Getting Started with UV/Vis Spectroscopy, Advanstar Communications, Cleveland, OH, 1996. Co-author: J. Workman

Academic Press Handbook of Molecular Spectroscopic Techniques and Applications, "By Industrial Application" and "Flowing Systems: Chemical, Pharmaceutical, and Bio-Medical", J. Workman & A. Springsteen, Eds., Academic Press, New York, 1998.

Molecular Spectroscopy Workbench: Advances, Applications, and Practical Advice on Modern Spectroscopic Analysis, Wiley-Interscience, Inc., New York, 1998.

Near-Infrared Applications in Biotechnology, "Biomedical Applications" and "Pharmaceutical Applications", R. Raghava, Rd., Marcel Dekker Inc., New York, 2000.

Encyclopedia of Pharmaceutical Technology, "Spectroscopic Methods of Analysis – Near Infrared Spectrometry", J. Swarbrick and J. Boylan, Eds., Marcel Dekker Inc., New York, 2001.

Handbook of Analytical Chemistry, "Anomalies in Near-Infrared Spectroscopy", J.M. Chalmers and P.R. Griffiths (Eds), John Wiley & Sons Ltd, Volume 5, pp. 2348-2354 (2002).

Handbook of Near-Infrared Analysis, 2nd ed. Revised and Expanded, Editor & Author, Marcel Dekker Inc., New York, 2001. Co-editor: D.A. Burns.

Near-Infrared Spectroscopy in Pharmaceutical and Medical Applications, Marcel Dekker Inc., New York, NY, 2002. Co-author: J.K. Drennen.

Method Development in Near-Infrared Spectroscopy, Marcel Dekker Inc., New York, NY, Summer 2003.

Application of Near-Infrared to Pharmaceutical Sysytems, Elsevier Publishing, Amsterdam, NL, Summer 2004.

Journal Articles:

"Quick Specific Assay for Aspirin", J. Pharm. Sci. 66, 139 (1977). Co-Author: E.E. Theimer.

"Determination of 1,4-Dioxane in Ethoxylated Surfactants", J. Soc. Cosmet. Chem. 31, 12 (1980). Co-author: J.J. Robinson.

"Identification of Actives in Multi-Component Pharmaceutical Dosage Forms via Near-IR Reflectance Analysis", Spectroscopy 1(1), 36 (1986). Co-author: T.A. Maldacker.

"Determination of Particle Size of Pharmaceutical Raw Materials Using Near-Infrared Reflectance Spectroscopy", Spectroscopy 1(7), 36 (1986). Co-authors: R.P. Torlini, M.P. Demkowitz.

"Use of Near Infrared in Pharmaceutical Analyses", Appl. Spectrosc. Rev. 23(1-2), 1987. (Invited)

"Analysis of Solid and Liquid Dosage Forms via NIRS", Spectroscopy 2(3), 36 (1987). Co-author: R.P. Torlini.

"Evaluation of a Near-IR Detector for HPLC", Spectroscopy 2(10), 33 (1987). Co-author: F.M.B. Weis.

"Determination of Enantiomeric Purity of Valine by Near Infrared Analysis", Spectroscopy 3(5), 25(1988). Co-authors: D. Honigs, B. Buchanan, A. Grunke.

"Design Parameters for a Near IR HPLC Detector", Spectroscopy 3(9), 56 (1988). Co-author: I.M. Vance.

"Near-IR Spectroscopy: What It is and What It is Not", Spectroscopy 4(2), 14 (1989).

"Two Valuable Tools for Instrument Evaluation..", Spectroscopy 4(8), 10(1989).

"A Novel Spectrometer Based on an Acousto-Optical Tunable Filter", Spectroscopy 5(1), 10 (1990).

"The Use of Near Infrared In Thin Layer Chromatography. Part I: Quantitative Applications", Spectroscopy 5(8), 38 (1990). Co-author: D.M. Mustillo.

"The Use of Near Infrared in Thin Layer Chromatography. Part II: Qualitative Applications", Spectroscopy 6(3), 26 (1991), Co-author: D.M. Mustillo.

"Further Parameters of a NIR/HPLC Detector. Part I: Limits of Analytical Sensitivity for Reverse Phase Chromatographic Systems", Spectroscopy 6(2), 12 (1991), Co-author: T.A. Dickinson.

"Further Parameters of a NIR/HPLC Detector. Part II: Non-Aqueous Solvents for Normal Phase and Size Exclusion Chromatography", Spectroscopy 6(7), 37 (1991).Co-Auth: T.A. Dickinson, W.R. Murphy.

"The Use of NIRS for Following the Dissolution of Multi-Component Pharmaceutical Dosage Forms", Proc. 3rd Internatl. Conf. on NIRS, Brussels, Belgium, June, 1991.

"Following The Progress of a Pharmaceutical Mixing Study via Near-Infrared Spectroscopy", Pharm. Tech. 15(9), 141 (1991).

"Near-Infrared Applications in Chemical Process Control", Measurements & Controls, Issue 149, October, 1991. (Invited)

"Near-Infrared Applications in the Pharmaceutical Industry", NIR News 2(4), 10 (1991). (Invited)

"Improving Pharmaceutical Quality Testing with NIRS", Pharm. Proc. Internatl., March, 1992. Co-authors: J.E. Carroll, S.E. Monfre. (Invited)

"Use of NIR in Thin Layer Chromatography", Appl. Spectrosc. Rev. 27(2), 125 (1992). Co-author: D.M. Mustillo. (Invited)

"NIR Spectroscopy: Theory and Applications", CHEMTECH 22(6), 74 (1992). (Invited)

"Letting You in on The Well-Kept Secret of Near-IR Spectroscopy", Today’s Chemist At Work 4(9), 30 (1995). (Invited)

"Use of Near-Infrared Spectroscopy in Cereal Products", Food Testing & Analysis 1(2), 35 (1995). (Invited)

"Comparison of NIR Spectrometers for Solid Dosage Forms", Pharm. Tech. [Tabletting & Granulation Yearbook] 21(10), 18 (1997). (Invited)

"In Situ Dissolution Testing Using a Fiber Optic Probe Dissolution System", Dissol. Tech. 6(4), 8 (1999). Co-authors: K. Bynum, E. Kraft, J. Pocreva, P. Palermo.

"After Twenty Years of Testing, Now It Is Time for Validation", Am. Pharm. Rev., 3 (3), 34 (2000). Co-Author: G.E. Ritchie.

"A General Test Method for the Development, Validation, and Routine Use of Disposable Near-Infrared Libraries", J. Near Infrared Spectrosc. 9, 165-184 (2001) Co-authors: C. Tso, G. Ritchie, L. Gehrlein

"Validation of a NIR Transmission Spectroscopic Procedure, Part A: Validation Protocols," J. Pharm. Biomed. Anal. 28 (2), 251-260 (2002). Co-authors: G. Ritchie, R. Roller, H. Mark, Cindy Tso, and S. MacDonald.

"Validation of a NIR Transmission Spectroscopic Procedure, Part B: Application to Alternate Content Uniformity and Release Assay Methods for Pharmaceutical Dosage Forms," J. Pharm. Biomed. Anal., 29 (1-2), 159-171(2002). Co-authors: G. Ritchie, R. Roller, H. Mark, Cindy Tso, and S. MacDonald.

"Growth of Near-Infrared Spectroscopy in Pharmaceutical and Medical Sciences," Proc. SPIE 4626, San Jose, CA , January 2002 (Invited-Keynote Address)

"Growth of Near-Infrared Spectroscopy in Pharmaceutical and Medical Sciences," Amer. Pharm. Rev., Winter, 2002.

PRESENTATIONS AND POSTERS: Emil W. Ciurczak

"Determination of Chloroacetate, Glycolate, and Chloride in Surfactant Reaction Mixtures via Ion Chromatography", PittCon, Atlantic City, March, 1979. Co-author: J.J. Robinson.

"Use of Pre-Columns for Analyzing Surfactant Mixtures via GLC", PittCon, Atlantic City, March, 1979. Co-author: J.J. Robinson.

"Determination of 1, 4-Dioxane in Ethoxylated Surfactants by GLC", PittCon, Atlantic City, March, 1980. Co-Author: J.J. Robinson.

"Determination of 1,4-Dioxane in Ethoxylated Surfactants via GLC" Society of Cosmetic Chemists, May, 1980. Co-author: J.J. Robinson. (Invited)

"Determination of Zinc in Animal Organs via DC Plasma Emission Spectroscopy", PittCon, Atlantic City, March, 1982. Co-author: R.V. Vivilecchia.

"Analysis of Raw Materials: Are We Ready for the 20th Century?" 24th Pharmaceutical Analysis Conference, Dells, WI, August, 1984. (Invited)

"Discriminant Analysis of Pharmaceutical Components using NIRA", 7th International. NIRA Symposium, Tarrytown, NY, July, 1984. (Invited)

"Determination of Hyoscyamine and Scopolamine in Dosage Forms via HPLC", PittCon, Atlantic City, March, 1984. Co-author: T. Shintani-Young.

"Identification of Polymeric Packaging Materials via NIRS", PittCon, New Orleans, March, 1985. Co-author: T. Shintani-Young

"Identification of Actives in Multi-Component Dosage Forms", PittCon, New Orleans, March, 1985. Co-author: T.A. Maldacker.

"Analysis of TLC Spots via NIRA", 8th International NIRA Symposium, Tarrytown, NY, August, 1985. (Invited)

"Qualitative Analysis of Pharmaceutical Materials via NIRA", PittCon, New Orleans, March, 1985.

"Investigation of Particle Size Effects on NIRA", FACSS, Philadelphia, October, 1985.

"Qualitative Uses of NIRA in Pharmaceutical Analysis", FACSS, Philadelphia, October, 1985.

"Qualitative and Quantitative Uses of NIRA in TLC", 1st Pan American Chemical Conference, San Juan, Puerto Rico, October, 1985.

"Identification of Isomers and Polymorphs via NIRA", 1st Pan American Chemical Conference, San Juan, Puerto Rico, October, 1985. Co-author: C. Kradjel.

"Particle Size Analysis by NIRA", 1st Pan American Chemical Conference, San Juan, PR, October, 1985.

"Quantitative Analysis of Pharmaceuticals via NIRS: Fact or Fiction?", 25th Pharmaceutical Analytical Conference, Merrimac, WI, July, 1986. (Invited)

"Discriminant Analysis of Pure Liquids via NIRS", 10th International Symposium on NIRA, Tarrytown, NY, September, 1986. (Invited)

"NIRS in Pharmaceutical Analysis: Do We Need Another Tool?", 1st National Meeting AAPS, Washington, DC, November, 1986. (Invited)

"Advantages and Limitations of a NIR Detector for LC", North Jersey Chromatography Discussion Group, Murray Hill, NJ, February, 1987. (Invited)

"Moisture Determination In Pharmaceutical Raw Materials by NIRA", PittCon, Atlantic City, March, 1987. Co-author: R.P. Torlini.

"Use of a NIR Detector in HPLC for Detection of Solutes Without Chromophores", PittCon, Atlantic City, March, 1987. Co-author: F.M.B. Weis.

"Characterization of Canvas and Paper in Art Works and Documents Using NIRA", PittCon, Atlantic City, March, 1987. Co-author: D.E. Honigs.

(Poster) "Physical Chemical Measurements via NIRS: Partial Molal Volumes, etc.", MARM (ACS), Stockton State College, NJ, May, 1987. Co-Author: J. Sze.

(Poster) "Advantages and Disadvantages of a NIR Detector for HPLC", MARM, Stockton State College, May, 1987. Co-Author: F.M.B. Weis.

"Analysis of Multi-Component Liquid Pharmaceutical Preparations Using Near-Infrared Spectroscopy", 27th EAS, New York, November, 1987. (Invited)

"Analysis of Drug Substances in Unknown Mixtures Using NIRS and the Method of Standard Additions", PittCon, New Orleans, March, 1988. Co-author: J. Sze.

"Reaction Kinetics of Drug Substances via NIRS", PittCon, New Orleans, 1988. Co-author: D. Zylinski.

"Use of NIR Detector for Analytical and Prep Scale LC of Amino Acids and Polymers", PittCon, New Orleans, 1988. Co-Author: I.M. Vance.

"General Correlation Charts for Compounds in the NIR Region", 4th International Conference on Diffuse Reflectance, Chambersburg, PA, August, 1988. (Invited)

"Design and Operation of a NIR Densitometer for Electrophoresis and TLC", PittCon, Atlanta, March, 1989. Co-author: D.M. Mustillo.

"Application of a NIR Detector in the HPLC of Amino Acids, Proteins, and Drug Substances", PittCon, Atlanta, March, 1989. Co-author: T.A. Dickinson.

"Construction and Application of a NIR Flow Cell Utilizing a Commercial NIR Spectrophotometer and Fiber Optics", 29th EAS, New York, September, 1989. Co-author: T.A. Dickinson.

"Performance Parameters of a NIR Densitometer for TLC", 16th FACSS, Chicago, October, 1989. Co-Author: D.M. Mustillo.

"The Quantitative and Qualitative Application of NIRS to Thin Layer Chromatography", PittCon, New York, March, 1990. Co-Author: D.M. Mustillo.

"The Use of NIRS in Normal Phase and Non-Aqueous Size Exclusion Chromatography", PittCon, New York, March, 1990. Co-Author: T.A. Dickinson.

PRESENTATIONS AND POSTERS: Emil Walter Ciurczak

"The Measurement of the Refractive Index of Liquids via NIRS Utilizing a Single Fiber Optic Probe", PittCon, New York, March, 1990. Co-Author: D.E. Honigs.

"The Use of NIRS for Following the Dissolution of Multi-Component Pharmaceutical Dosage Forms", 3rd International Conference on NIRS, Brussels, Belgium, June, 1990.

(Poster) "The Use of NIRS to Follow the Uniformity of Mixing in a Pharmaceutical Blend", American Association of Pharmaceutical Scientists 6th National Meeting, Las Vegas, November, 1990.

(Poster) "Dissolution Studies of Multi-component Dosage Forms Utilizing NIRS", American Association of Pharmaceutical Scientists 6th National Meeting, Las Vegas, November, 1990.

"Identification and Quality Assessment of Incoming Raw Materials and Pharmaceutical Mixtures", American Association of Pharmaceutical Scientists 6th National Meeting, Las Vegas, November, 1990.

"Use of NIRS in Pharmaceutical Mixing Studies With or Without a priori Knowledge of the Individual Components", 30th EAS, Somerset, NJ, November, 1990. (Invited)

"Novel Applications of NIRS", Spectroscopic Society of Pittsburgh, January, 1991 (Invited).

"Use of NIRS for the Identification of Drugs of Abuse on TLC Plates", PittCon, Chicago, March, 1991. Co-Author: D.M. Mustillo.

(Poster) "Determination of Optical and Stereo-Isomers via NIR/HPLC", PittCon, Chicago, March, 1991.

"Applications of NIRS in Liquid and Thin-Layer Chromatography", North Jersey Chromatography Topical Group, South Orange, NJ, September, 1991. (Invited)

"Analysis of Intact Tablets and Capsules by NIRS", 30th Eastern Analytical Symposium, Somerset, NJ, November, 1991. (Invited)

(Poster) "Non-Destructive, Single-Tablet Analysis via Near-Infrared Spectroscopy", AAPS National Meeting, Washington, DC, November, 1991.

"Identification of Single Tablets and Capsules Utilizing Near-Infrared Spectroscopy", AAPS National Meeting, Washington, DC, November, 1991.

"Near-IR: What is it and What Does it Do?", SAS (Baltimore- DC Section) Meeting, Washington, DC, February, 1992. (Invited)

"Novel Chromatographic Applications of NIR Spectroscopy", PittCon, New Orleans, March, 1992. (Invited Symposium)

"Determination of Concentrations of Individual Components in Overlapping HPLC Peaks Using Near-IR Spectroscopy", PittCon, New Orleans, March, 1992.

"Analysis of Individual, Intact Tablets and Capsules for Pharmaceutical Analyses Using Near-Infrared Spectroscopy", PittCon, New Orleans, March, 1992.

"On-Line Applications of NIRS in Pharmaceutical Processing", SPIE Regional Conference, New Brunswick, NJ, March, 1992. (Invited)

 "The Use of a NIR Detector for Prep Scale Chromatography", 16th International Symposium on Column LC, Baltimore, June, 1992.

"Use of a NIR Detector for Size Exclusion Chromatography", 16th International Symposium on Column LC, Baltimore, June, 1992.

"Some Forensic Applications of Near-IR Spectroscopy", EAS, Somerset, NJ, November, 1992. (Invited)

"Applications of a Diode-Array NIR Spectrometer to Solid Dosage Forms", EAS, Somerset, NJ, November 1992. Co-Author: J.M. Pope. (Invited)

"Determination of Enantiomer Ratios in Racemic Mixes Using NIRS", Pittcon, Atlanta, March, 1993. Co-Authors: W.R. Murphy, L.J. Cline-Love.

"Influence of Physical Tablet Parameters on the NIR Analysis of Intact Tablets", Pittcon, Atlanta, March, 1993. Co-Authors: E.W. Richmond, G.A. Duff.

"Analysis of Intact Pharmaceutical Tablets Using a Diode-Array NIR Spectrometer", Pittcon, Atlanta, March, 1993. Co-Author: J.M. Pope.

"A Universal NIR Library for World-Wide Identification of Raw Materials", Pittcon, Atlanta, March, 1993. Co-Author: J. Giambra.

"Real-Time Identification of Incoming Raw Materials", PharmAnalysis ‘'93, E. Brunswick, NJ, June, 1993. (Invited)

(Poster) "Speciation of Racemic Solutes in LC Using a NIR Detector", EAS, Somerset, NJ, 1994. Co-Authors: L.J. Cline-Love, W.R. Murphy

"Confirmation of NIR/LC Detector Capabilities Using Molecular Modeling", PittCon, Atlanta, 1994. Co-Authors: L.J. Cline-Love, W.R. Murphy.

"Identification of Proper Instrument(s) for On-Line Analyses", PharmAnalysis '94, Atlantic City, June, 1994. (Invited) (Session Chair)

"Process Applications of NIR in the Pharmaceutical Industry", 7th International Diffuse Reflectance Conference (IDRC), Chambersburg, PA, Aug., 1994 (Invited)

"Progress in Application of Near-Infrared as a Detector for HPLC and TLC", Soc. Appl. Spec., Baltimore-Washington Section, Washington, DC, March, 1996. (Invited)

"Effect of Dielectric Constant, Salt Concentrations, and Ionization of Weakly Dissociating Molecules on the NIR Spectra of Solutes in Aqueous Solutions", 8th IDRC, Chambersburg, PA, August, 1996. (Invited)

"Blending Studies and Homogeneity of Pharmaceutical Mixtures", ISPE Annual Meeting., Marco Island FL, November, 1997. (Invited)

"Comparison of Commercial NIR Spectrometers Used to Analyze Solid Pharmaceutical Dosage Forms", PittCon, New Orleans, LA, March, 1998.

"Latest Innovations in Pharmaceutical Analyses using Near-Infrared Spectroscopy", 37th Pharmaceutical Analytical Conference (Land O’ Lakes), Merrimac, WI, August, 1998. (Invited)

A Remote Reflectance (IR) Probe for Determining the Cleanliness of Reactor Walls: A Comparison with Current FDA-Approved Methods", FACSS, Austin, TX, October 1998. Co-author: M. Druy

"A Remote Reflectance (IR) Probe for Determining the Cleanliness of Reactor Walls: A Comparison with Clean and Swab Methods", EAS, Somerset, NJ, November 1998. Co-author: M. Druy

"Some Applications of NIRS in the Pharmaceutical Industry" NY Chapter of SAS, Suffern, NY April, 1999. (Invited)

"Validation Issues in Implementing Near-IR as an In-Process Pharmaceutical Production Tool", SPQ-99, East Brunswick, NJ, June, 1999. (Invited)

"Validating a Near-Infrared Spectroscopic Method", SPQ-99, East Brunswick, NJ, June, 1999. Co-author: G. Ritchie (Poster)

"NIR Analysis of Solid and Liquid Dosage Forms: Software and Chemometric Applications", 8th Argentine Industrial Congress of Pharmacy and Biochemistry, Beunos Aires, June, 1999. (Invited)

"Use of NIR Transmission Analysis At-Line for Release of Solid Dosage Forms", 14th International Forum Process Analytical Chemistry (IFPAC), Lake Las Vegas, January, 2000. Co-Author: G. Ritchie. (Invited)

"In Situ Fiber Optic Dissolution Apparatus for Process Control", 14th International Forum Process Analytical Chemistry (IFPAC), Lake Las Vegas, January, 2000. Co-Author: K. Bynum. (Invited)

"Simultaneous Devel., Validation, and Implementation of a NIR Diffuse Reflectance ID Method for Pharm. Active and Placebo Clinical Dosage Forms", PittCon, New Orleans, March, 2000. Co-Author: G. Ritchie.

"Validation of a NIR Transmission Assay of Continuous Release Prescription Analgesic Tablets", PittCon, New Orleans, March, 2000. Co-Author: G. Ritchie.

"Development and Application of a Fiber Optic Dissolution System", PittCon, New Orleans, March, 2000. Co-Author: K. Bynum, G. Ritchie, S. Hashemi, G. Sweerus, A. Kassis, and P. Palermo. (poster)

"Applications of a 2-D Near-IR Imaging in Pharmaceutical Analysis", PittCon, New Orleans, March, 2000. Co-Author: G. Ritchie and K. Bynum.

"Analytical Instrumentation: It’s 2000: So, Now What Do We Do for an Encore?", SKB Analytical Sciences Colloquium, New Brunswick, NJ, October, 2000. (Invited)

"Assessing the Calibration Transfer Between Two Scanning NIR Spectrometers Using Sustained Release Prescription Analgesic Tablets", EAS, Atlantic City, Nov., 2000. Co-Author: G. Ritchie, C. Tso.

"Real World NIR Applications for Solving Pharmaceutical Problems", EAS, Atlantic City, Nov., 2000. Co-Author: C. Tso, G. Ritchie. (Poster)

"New Chemometric Software for Process Equation Generation", IFPAC, Amelia Island, FL, January 2001.

"Near-Infrared: After 20 years of Testing, It’s Time for Validating", Near-Infrared Validation Workshop, Tarrytown, New York, March 2001. (Invited)

"Methodologies and Strategies of Blend Uniformity Studies", 3rd Annual Blend Uniformity Conf., Arlington, VA, December, 2001. (Invited)

"The Growth of NIRS in Pharmaceutical and Medical Sciences", SPIE Meeting, San Jose, CA, January 2002. (Invited: Keynote Speaker & Session Chair).

"NIR Spectroscopy: Where we are, where we’re going, and what speed-bumps we may hit along the way", Frontiers in NIR Spectroscopy Session (Coblentz Society Sponsored), EAS, Somerset, NJ November 2002. (Invited)

"Process Analysis Technologies (PAT): Near-IR", Conf. on Anal. Meth. & Gen. USP Topics, Phila, PA, Feb, 2003. (Keynote, invited)

"PAT: What is Needed to Break the Deadlock", Pat (Barnett) Conference, Phila, PA, March 2003.

"PAT: What is Needed to Break the Deadlock", PAT-IVT Conference, Brussells, Belgium, June 2003.

"Process Analytical Technologies (PAT) and Current Regulations" Regulatory and Quality Topical Group of the North Jersey Section of the ACS, Morristown, NJ June 2003.

"Applications of NIR in Pharmaceutical Materials Analyses", 4th Internat’l Workshop on Phys. Characterization of Pharm. Solids, Stamford, CT, June, 2003.

NIR, IR, Raman Workshop, 4th Internat’l Workshop on Phys. Characterization of Pharm. Solids, Stamford, CT, June, 2003.

"Process Analytical Technologies (PAT) and Current Regulations", Regulatory and Quality Sub-Section of NJ-ACS, Morristown, NJ, June 2003.

"PAT: What is Needed to Implement it now", 2003 PDA/FDA Joint Regulatory Conference, Washington, DC, September, 2003.

NIR Short Course: Advanced Topics, FACSS Meeting, Ft. Lauderdale, FL, October, 2003.

PAT Workshop, FACSS Meeting, Ft. Lauderdale, FL, October, 2003. with J. Carroll